In Vitro Fertilization (IVF)

Many people encounter setbacks in their pursuit of building a family. IVF treatment can help you overcome these obstacles.

Drs. Nurit Winkler and Marc Kalan offer compassionate, fully personalized care, and will guide you through the entire treatment process.

Learn how IVF treatment at our clinics in Bakersfield and Encino, CA, has helped patients throughout California and beyond experience the joys of parenthood.

What Is in Vitro Fertilization?

In vitro fertilization is a process in which a woman’s eggs (oocytes) are removed and combined with sperm in a laboratory environment. The resulting embryo is then transferred to the uterus in order to be carried to term.

Helping You Realize Your Dreams

We are a team of California fertility specialists dedicated to helping our patients begin and expand their families. Our clinic combines advanced technology, intensive training, and compassion to successfully conceive and deliver a healthy baby.

What Can IVF Treat? Overcoming Infertility and Other Setbacks

Female Factor Infertility

Female factor infertility includes conditions that affect the health of the ovaries, uterus, or fallopian tubes, such as polycystic ovarian syndrome (PCOS), endometriosis, diminished ovarian reserve (DOR), and premature or early menopause.

Male Factor Infertility

Examples of male factor infertility include low sperm count (oligospermia), poor sperm motility that impairs their ability to reach the fallopian tubes, abnormal sperm morphology, and the total absence of viable sperm in the semen (azoospermia).

Mixed Infertility

Mixed infertility describes a combination of male factor infertility and female factor infertility. Female, male, and mixed infertility each account for approximately one-third of all cases of infertility seen at clinics across the country.

Unexplained Infertility

In very rare cases, there is no identifiable reason why a couple or individual cannot become pregnant. The patient may be in good general and reproductive health, but is simply unable to conceive through natural means.

The History of IVF Did You Know...


The first human conceived through IVF treatment was Louise Brown, born in 1979 in Lancashire, England. At that time, IVF was specifically designed to help patients where the female partner had an obstruction (blockage) in her fallopian tubes, also known as tubal factor infertility. The blockage stopped sperm and egg from meeting and thus prevented a pregnancy. Through IVF, doctors brought the sperm and egg together and facilitated fertilization. Since then, IVF treatment has been used to address a wide array of issues affecting both male and female fertility.

Are You Interested in IVF? Contact Our Encino Fertility Clinic to Learn More

If you've struggled to grow your family, you are not alone. Dr. Winkler and Dr. Kalan have helped countless patients throughout Encino, Los Angeles, and Bakersfield, CA, bring new life into this world and experience the joys of raising a child.

We understand the frustrations of this journey, which is why we'll strive to be as patient and compassionate as possible throughout every step of the process. Our fertility specialists will work closely with you, answering any questions you may have and making sure you fully understand the pros and cons of the IVF process. You can reach out whenever concerns arise, and we will provide the support and care you need.

To learn more about in vitro fertilization, contact our fertility centers online. You can also reach the Los Angeles Reproductive Center by phone at:

(818) 946-8051

Drs. Marc Kalan and Nurit Winkler
Dr. Kalan and Dr. Winkler look forward to meeting you.

A 5-Star Review from a Satisfied Patient Patients Share Their Success Stories

"I’m so grateful that I found this place   and that after my second IUI, I became pregnant. Thank you to Dr. Kalan, Dr. Winkler, and Nurse Kimberly for your expertise, care, and kindness. I’m blessed to be expecting a baby boy next year. Thanks again for all that you do Robyn Elizabeth

How Much Does In Vitro Fertilization Cost?

The cost of in vitro fertilization can vary based on a number of factors, including the fertility drugs used, additional treatments, and the need for multiple IVF cycles. During your visit to the Los Angeles Reproductive Center, we can provide a full price breakdown and outline different payment options.

Ideal candidates for IVF treatment include people who...

How Effective Is IVF?


The success rates for IVF treatment can vary based on a number of factors, including the age of the parents and the presence of certain medical conditions that affect fertility. According to the American Pregnancy Association, the average success rate of live birth from IVF for women under 35 is 41-43%. This is notably higher than artificial insemination procedures, including modern techniques like intrauterine insemination (IUI).

Do You Have Questions About IVF? Contact Our Fertility Specialists

Do you want to know more about the advantages and disadvantages of IVF treatment? Dr. Winkler and Dr. Kalan are here to help. They have assisted countless families throughout the greater Los Angeles area, including Encino and the San Fernando Valley. Our team is ready to listen to you.

For more information about in vitro fertilization, contact us online. Our clinic has fertility offices in Encino and Bakersfield. You can also schedule a consultation by phone.

Call Our Fertility Centers Today

(818) 946-8051

"I can't complain about Dr Kalan. He was very sweet, responsive, knowledgeable, and caring about his work and his patients. If there was a problem he wanted to be thorough and would talk to you about any additional testing he recommended to be done. He spoke in ways that helped me understand things. He even gave me a call after my baby was born to see how we were doing. He called me on more than one occasion if there was something that i needed to do and/or know. I even sometimes had issues paying for some things and he would help me financially. 100% i recommend Dr Kalan. its because of him i have my beautiful rainbow baby! Thank you Dr Kalan for helping us on our journey to parenthood!! You truly are a blessing!!" Melie Sin

The Risks and Benefits of IVF

Risks of IVF Treatment

The most common risks of IVF treatment include the possibility of multiple births (twins or triplets), ovarian hyperstimulation syndrome (OHSS), and adverse reactions to the fertility drugs used during the process.

Benefits of IVF Treatment

The main benefits of IVF treatment include the increased chances of pregnancy and live birth, the reduced risk of pregnancy loss, and the high level of control over eggs, sperm, timing, and other pregnancy variables.

Preparing for an IVF Cycle

We help patients prepare for their IVF cycle in order to increase the chances of success. In addition to reproductive viability screenings, we also focus on your nutrition, supplementation options, and emotional well-being.

The In Vitro Fertilization Process

Ovarian Stimulation

Fertility medication is used to increase the number of eggs produced during a patient's cycle.


During office visits, we use ultrasounds and blood tests to monitor the egg follicles.

Egg Retrieval

After inducing ovulation, we perform a simple outpatient procedure to harvest viable eggs from the ovaries.


The harvested eggs are fertilized and allowed to incubate in a safe laboratory setting.

Embryo Transfer

During the embryo transfer phase, viable embryos are placed into the uterus to implant and continue developing.

In Vitro Fertilization (IVF)

Why Egg Retrieval Is Crucial


Egg retrieval is an important step of the process, allowing us to retrieve mature eggs that can be fertilized or preserved for later use. Dr. Winkler and Dr. Kalan work to ensure the comfort and safety of patients during the procedure. We also monitor patients afterward as the anesthesia wears off to ensure their well-being before they return home.

Mini IVF and Natural IVF

In addition to traditional in vitro fertilization, there are different ways of performing the procedure.

Mini IVF

Also known as minimal stimulation IVF and micro IVF, mini IVF treatment uses weaker medications or smaller dosages of fertility drugs during ovarian stimulation.

Natural IVF

Another variation on conventional in vitro fertilization, natural IVF treatment uses no drugs whatsoever during the ovarian stimulation phase of the treatment process.

Learn More About Your Fertility Treatment Options Contact the Los Angeles Reproductive Center

If you've struggled to grow your family, you should speak with Dr. Winkler and Dr. Kalan. Together, they've helped countless people overcome their reproductive health issues. They proudly serve Los Angeles and its surrounding communities, including Encino, and Bakersfield, CA.

For more information about in vitro fertilization, contact our fertility clinics today. You can also reach the Los Angeles Reproductive Center by phone.

Call Our Fertility Centers

(818) 946-8051

"Both doctors we saw and all the staff were very professional, lovely to interact with and we felt like they cared for us during the whole process.  We were luckily to find such a wonderful clinic and blessed with two beautiful children. Thank you so much" Andrew Hewett

IVF for LGBTQ Couples

Dr. Winkler and Dr. Kalan offer a wide array of services that help same-sex couples experience the exhilaration of pregnancy and childbirth. In vitro fertilization plays a key role.

IVF Treatment for Male Couples

For same-sex male couples, one or both fathers' sperm can be mixed with eggs from an egg donor. A surrogate is then selected who will carry the fertilized egg to term for the couple.

IVF Treatment for Female Couples

For same-sex female couples, donor sperm is used in an IVF cycle. We can then perform embryo transfer so one of the mothers can carry their baby to term. Egg donors and surrogates can also be used when needed.

We can discuss your needs and what treatments will be required during the consultation process.

Pregnant woman and female partner smiling while holding a sonogram photo
Dr. Winkler and Dr. Kalan are proud to help LGBTQ patients throughout the greater Encino and Los Angeles area.

IVF with Egg Donors and Sperm Donors

Diminished ovarian reserve, a lack of viable eggs, low sperm count, and poor sperm motility can all have a negative effect on the ability to become pregnant. When patients lack viable eggs or sperm, it's possible to work with a donor. LGBTQ families can also benefit from using donors.

Egg donors and sperm donors are carefully screened for health and wellness, and cataloged based on a number of genetic traits as well as their professional and personal interests.

Our team of fertility specialists can help you find an egg donor or sperm donor in the Los Angeles and Encino area that meets your needs. We'll also address any concerns you may have about the IVF process using donor eggs or sperm.

Surrogacy Options How In Vitro Fertilization Plays a Role

If a patient cannot carry a child to term themselves, a surrogate can do so on their behalf. The Los Angeles Reproductive Center can help you select a surrogate who meets your criteria.

Additional Fertility Services Enhancing the IVF Process

In addition to egg freezing, we offer other services that can potentially boost the success rate of an IVF cycle...

Preimplantation Genetic Diagnosis (PGD)

PGD is a type of genetic test performed on embryos before embryo transfer. The procedure monitors for chromosome abnormalities or genetic disorders that could put the pregnancy at risk. By performing PGD, we can ensure that ideal embryos are used during embryo transfer.

Intracytoplasmic Sperm Injection (ICSI)

ICSI is an assisted reproductive technology procedure that increases the chances of successful fertilization when sperm is unable to penetrate the outer layer of the egg. This may be due to poor sperm quality or low sperm motility. During ICSI, a single sperm is injected directly into a viable egg.

In Vitro Fertilization FAQs We Have the Answers You're Looking For

Couple speaking with doctor

The Los Angeles Reproductive Center can answer any questions you may have about fertility treatments.

In vitro fertilization is a complicated process. It's no surprise we receive so many questions about the procedure, whether it be about success rates, what happens during egg retrieval and embryo transfer, or the potential benefits of ICSI.

Whatever questions you may have about IVF treatment, the Los Angeles Reproductive Center has answers. We've compiled a list of the most common questions about in vitro fertilization we hear at our clinics in Encino and Bakersfield, such as:

  • Is IVF treatment safe?
  • Will insurance cover IVF treatment?
  • Is the risk of multiple births like twins and triplets high?

Check out our IVF FAQ page, and feel free to contact our fertility clinics if you have any other questions about assisted reproductive technology.

Make Your Dreams Come True California Patients Share Their Success Stories

Dr. Kalan is the best doctor we have ever met. He’s a professional, ability, knowledgeable, friendly, patience and responsible doctor.
We are so lucky to find him. We have a twins now."
Selina Pi
Los Angeles Reproductive Center office

Los Angeles Reproductive Center

Los Angeles Reproductive Center is a state-of-the-art fertility center offering the latest fertility testing and treatment options. Our fertility specialists, Dr. Nurit Winkler and Dr. Marc Kalan, are double board-certified doctors who have been widely recognized for their contributions to reproductive medicine. 

To help all patients achieve their dreams of parenthood, our doctors offer:

  • Compassionate care
  • Flexible payment options
  • Two conveniently located offices

Schedule a consultation online or call us at (818) 946-8051 to learn more about our fertility treatments.

Reach Out To Us Today

Los Angeles Reproductive Center is a unique fertility clinic focused on treating patients like family and built upon the principles of communication, compassion, warmth, openness, and service that accompanies an exceptional pregnancy rate. Contact us today to schedule an appointment.

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16055 Ventura Blvd
Ste 1127
Encino, CA 91436

Open Today 8:00am - 5:00pm

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Bakersfield Office

8305 Brimhall Rd
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Bakersfield, CA 93312

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