(818) 477-1051 Book Now
A joyful family moment.

Genetic Testing of Embryos

Combining cutting-edge technology and thoughtful analysis, genetic testing  can help you have a healthier pregnancy.

Book Now
A happy family on the couch

What is preimplantation genetic testing (PGT)?

PGT involves running tests on each embryo to select the best embryo to transfer before it is placed into the uterus. This may help to increase the chance of a healthy pregnancy by reducing the risk of implanting an embryo with genetic or chromosomal abnormalities. This process can also decrease chances of miscarriage, which is often associated with chromosomal issues in the embryo. PGT also identifies the gender of each embryo, which can be used for gender selection.

Book Now

How PGT treatment works

After your embryos grow for 5-7 days in our lab, our embryologists will biopsy your embryos and send the sample to a PGT lab to run one or more of the following tests:


  • PGT-A (Preimplantation Genetic Testing for Aneuploidy): This test examines the chromosomes of each embryo and identifies embryos with an abnormal number of chromosomes (aneuploid embryos). Transferring an embryo with the normal chromosomal count may increase the chance of implantation and lower the risk of miscarriage. With this test it’s also possible to determine the sex of the embryo.

  • PGT-M (Preimplantation Genetic Testing for Monogenic Disorders): This genetic test is available for couples in which genetic testing identifies a genetic mutation that can be transmitted to the child, resulting in a genetic disease.

  • PGT-SR (Preimplantation Genetic Testing for a Structural Rearrangement): This is a test that screens for structural issues in the chromosomes that form an abnormal embryo and can significantly increase the risk of miscarriage.
round vials of reddish liquid
baby on mother's lap playing upside down

Is PGT right for me?

Whether you should pursue preimplantation genetic testing is based on a number of factors including your age, genetic background, medical history and test results. Ultimately, PGT-A may improve the chances of a successful pregnancy and reduce the risk of miscarriage for many patients undergoing IVF. Knowing which embryos may result in miscarriage or abnormal pregnancy gives you more information and autonomy on your fertility journey.

"[We did] 2 egg retrievals and our second FET was successful- we're expecting now! We couldn't be happier as we thought this may not be possible with all of our complications."

Genetic Testing patient via Yelp

Book Now

Paying for PGT

Though coverage for fertility care varies widely by insurance plan, the good news is that you have options. We are committed to guiding you through your insurance benefits, out-of-pocket expenses, and other financing options every step of the way. With Los Angeles Reproductive Center you will never be in the dark about cost.

LEARN MORE ABOUT COSTS
Smiling baby boy

Your next chapter starts here. We’re here to help you write it.

Book Now

You’ve got questions, we’ve got answers.

Embryos with an abnormal number of chromosomes usually do not implant, or start to implant but result in a miscarriage. They can also result in a child with chromosomal issues such as Down’s Syndrome. PGT-A identifies the embryos most likely to implant normally so that the transfer of a single embryo is more likely successful. Especially for women over 35 and those with recurrent pregnancy losses, PGT-A allows us to transfer just one healthy embryo with the best chance of pregnancy and the lowest chance of miscarriage.

Current evidence suggests that the biopsy for PGT does not harm the embryo if performed by skilled embryologists. A very small number of cells are removed from an area that will eventually grow into the placenta. The inner cell mass, which is the part of the embryo that will become the baby, is not touched. At LARC, we perform PGT on more than 90% of our embryos and our embryologists are very experienced at performing the procedure.

PGT-M may be appropriate when intended parents are at high risk of having a child with a serious genetic disease. If family history or genetic carrier screening suggest high risk, we will refer you to a genetic counselor to discuss next steps.

PGT-A can be used to select the gender of the embryo being transferred. Many patients who are interested in gender selection come to Los Angeles Reproductive Center to build or complete their families.