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In Vitro Fertilization (IVF)

Many people encounter setbacks in their pursuit of building a family. IVF treatment can help you overcome these obstacles.

Drs. Nurit Winkler and Marc Kalan offer compassionate, fully personalized care, and will guide you through the entire treatment process.

Learn how IVF treatment has helped people throughout Encino, Los Angeles, and Bakersfield, CA, experience the joys of parenthood...

What Is In Vitro Fertilization?

In vitro fertilization is a process in which a woman’s eggs (oocytes) are removed and combined with sperm in a laboratory environment. The resulting embryo is then transferred to the uterus in order to be carried to term.

Helping You Realize Your Dreams

We are a team of fertility specialists dedicated to helping our patients begin and expand their families. We combine advanced technology, intensive training, and compassion to successfully conceive and deliver a healthy baby.

Dr. Winkler and Dr. Kalan are fully committed to you...

Are You Interested in IVF? Contact Our Fertility Clinic to Learn More

If you've struggled to grow your family, you are not alone. Dr. Winkler and Dr. Kalan have helped countless patients throughout Encino, Los Angeles, and Bakersfield, CA, bring new life into this world and experience the joys of raising a child.

We understand the frustrations of this journey, which is why we'll strive to be as patient and compassionate as possible throughout every step of the process. Our fertility specialists will work closely with you, answering any questions you may have and making sure you fully understand the pros and cons of the IVF process. You can reach out whenever concerns arise, and we will provide the support and care you need.

To learn more about in vitro fertilization, contact our fertility centers online. You can also reach the Los Angeles Reproductive Center by phone at:

(818) 946-8051

Dr. Marc Kalan and Dr. Nurit Winkler
Dr. Kalan and Dr. Winkler look forward to meeting you.

5-Star Reviews from Satisfied Patients Putting Your Needs and Goals First


Ashley Jebbia


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Dr. Kalan is the most amazing doctor I have ever had! He truly cares about his patients and I cannot say enough good things about him. I wish I could see him throughout my whole pregnancy! But he is so amazing and he is always there for any questions or concerns I have. Thank you, Dr. Kalan, for being an exceptional, caring doctor!

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Lotta Langstrumpf


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Dr. Winkler is the best doctor we ever met before! We did an IVF for surrogacy with her and we are so thankful of what she did for us. Dr. Winkler and her team are very sympathetic, nice and communication was perfect. We always felt safe and understood, because of her sensitive way and well prepared for everything. We would definitely recommend it to everyone!

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The History of IVF Did You Know...


The first human conceived through IVF treatment was Louise Brown, born in 1979 in Lancashire, England. At that time, IVF was specifically designed to help patients where the female partner had an obstruction (blockage) in her fallopian tubes, also known as tubal factor infertility. The blockage stopped sperm and egg from meeting and thus prevented a pregnancy. Through IVF, doctors brought the sperm and egg together and facilitated fertilization. Since then, IVF treatment has been used to address a wide array of issues affecting both male and female fertility.

What Can IVF Treat? Overcoming Infertility and Other Setbacks

Female Factor Infertility

Female factor infertility includes conditions that affect the health of the ovaries, uterus, or fallopian tubes, such as polycystic ovarian syndrome (PCOS), endometriosis, diminished ovarian reserve (DOR), and premature or early menopause.

Male Factor Infertility

Examples of male factor infertility include low sperm count (oligospermia), poor sperm motility that impairs their ability to reach the fallopian tubes, abnormal sperm morphology, and the total absence of viable sperm in the semen (azoospermia).

Mixed Infertility

Mixed infertility describes a combination of male factor infertility and female factor infertility. Female, male, and mixed infertility each account for approximately one-third of all cases of infertility seen at clinics across the country.

Unexplained Infertility

In very rare cases, there is no identifiable reason why a couple or individual cannot become pregnant. The patient may be in good general and reproductive health, but is simply unable to conceive through natural means.

Ideal candidates for IVF treatment include people who...

IVF for LGBTQ Couples

Dr. Winkler and Dr. Kalan offer a wide array of services that help same-sex couples experience the exhilaration of pregnancy and childbirth. In vitro fertilization plays a key role.

IVF Treatment for Male Couples

For same-sex male couples, one or both fathers' sperm can be mixed with eggs from an egg donor. A surrogate is then selected who will carry the fertilized egg to term for the couple.

IVF Treatment for Female Couples

For same-sex female couples, donor sperm is used in an IVF cycle. We can then perform embryo transfer so one of the mothers can carry their baby to term. Egg donors and surrogates can also be used when needed.

We can discuss your needs and what treatments will be required during the consultation process.

Pregnant woman hugging female partner
Dr. Winkler and Dr. Kalan are proud to help LGBTQ patients throughout the greater Encino and Los Angeles area.

The Risks and Benefits of IVF

Risks of IVF Treatment

The most common risks of IVF treatment include the possibility of multiple births (twins or triplets), ovarian hyperstimulation syndrome (OHSS), and adverse reactions to the fertility drugs used during the process.

Benefits of IVF Treatment

The main benefits of IVF treatment include the increased chances of pregnancy and live birth, the reduced risk of pregnancy loss, and the high level of control over eggs, sperm, timing, and other pregnancy variables.

How Much Does In Vitro Fertilization Cost?

The cost of in vitro fertilization can vary based on a number of factors, including the fertility drugs used, additional treatments, and the need for multiple IVF cycles. During your visit to the Los Angeles Reproductive Center, we can provide a full price breakdown and outline different payment options.

Do You Have Questions about IVF? Contact Our Fertility Specialists

Do you want to know more about the advantages and disadvantages of IVF treatment? Dr. Winkler and Dr. Kalan are here to help. They have assisted countless families throughout the greater Los Angeles area, including Encino and Bakersfield, CA. Our team is ready to listen to you.

For more information about in vitro fertilization, contact our fertility clinics online. You can also schedule a consultation by phone.

Call Our Fertility Centers Today

(818) 946-8051

"Dr. Kalan is the most amazing doctor!! I cannot say enough good things about him and the staff. Dr. Kalan helped me conceive my daughter, who is now almost two years old, and he also helped me conceive my second child, who I am now pregnant with--both through IVF. We started by trying IUI, but we weren’t successful, so we then went to IVF. There have been ups and downs and joys and disappointments over the last few years with me trying to conceive, and Dr. Kalan has been with me every step of the way.

"He is so sensitive and great at dealing with every situation. He really takes the time to talk to you and explain every detail. He has always made himself available to me, even when I had questions after hours. And he has a wonderful bedside manner. It’s easy and convenient to make appointments, and the staff is pleasant and sensitive to all situations. I highly recommend Dr. Kalan. I wouldn’t use anyone else!"
Gina B.

How Effective Is IVF?


The success rates for IVF treatment can vary based on a number of factors, including the age of the parents and the presence of certain medical conditions that affect fertility. According to the American Pregnancy Association, the average success rate of live birth from IVF for women under 35 is 41-43 percent. This is notably higher than artificial insemination procedures, including modern techniques like intrauterine insemination (IUI).

Couple at ultrasound appointment Couple at ultrasound appointment

Preparing for an IVF Cycle

We help patients prepare for their IVF cycle in order to increase the chances of success. In addition to reproductive viability screenings, we also focus on your nutrition, supplementation options, and emotional well-being.

The In Vitro Fertilization Process

Ovarian Stimulation

Fertility medication is used to increase the number of eggs produced during a patient's cycle.


During office visits, we use ultrasounds and blood tests to monitor the egg follicles.

Egg Retrieval

After inducing ovulation, we perform a simple outpatient procedure to harvest viable eggs from the ovaries.


The harvested eggs are fertilized and allowed to incubate in a safe laboratory setting.

Embryo Transfer

During the embryo transfer phase, viable embryos are placed into the uterus to implant and continue developing.

In Vitro Fertilization (IVF)

Why Egg Retrieval Is Crucial


Egg retrieval is an important step of the process, allowing us to retrieve mature eggs that can be fertilized or preserved for later use. Dr. Winkler and Dr. Kalan work to ensure the comfort and safety of patients during the procedure. We also monitor patients afterward as the anesthesia wears off to ensure their well-being before they return home.

In addition to traditional in vitro fertilization,
there are different ways of performing the procedure...

Mini IVF and Natural IVF

Mini IVF

Also known as minimal stimulation IVF and micro IVF, mini IVF treatment uses weaker medications or smaller dosages of fertility drugs during ovarian stimulation.

Natural IVF

Another variation on conventional in vitro fertilization, natural IVF treatment uses no drugs whatsoever during the ovarian stimulation phase of the treatment process.

Learn More about Your Fertility Treatment Options Contact the Los Angeles Reproductive Center

If you've struggled to grow your family, you should speak with Dr. Winkler and Dr. Kalan. Together, they've helped countless people overcome their reproductive health issues. They proudly serve Los Angeles and its surrounding communities, including Encino, and Bakersfield, CA.

For more information about in vitro fertilization, contact our fertility clinics today. You can also reach the Los Angeles Reproductive Center by phone.

Call Our Fertility Centers

(818) 946-8051

IVF with Egg Donors and Sperm Donors

Diminished ovarian reserve, a lack of viable eggs, low sperm count, and poor sperm motility can all have a negative effect on the ability to become pregnant. When patients lack viable eggs or sperm, it's possible to work with a donor. LGBTQ families can also benefit from using donors.

Egg donors and sperm donors are carefully screened for health and wellness, and cataloged based on a number of genetic traits as well as their professional and personal interests.

Our team of fertility specialists can help you find an egg donor or sperm donor in the Los Angeles and Encino area that meets your needs. We'll also address any concerns you may have about the IVF process using donor eggs or sperm.

Sperm and eggs

Surrogacy Options How In Vitro Fertilization Plays a Role

If a patient cannot carry a child to term themselves, a surrogate can do so on their behalf. The Los Angeles Reproductive Center can help you select a surrogate who meets your criteria.

"Dr. Winkler is the best of the best! After seeing several doctors before finding her, Dr. Winkler was the only one who was compassionate, positive, and worked tirelessly to find a solution to start our family. She never made us feel like ours was a problem that couldn't be solved.

"She is extremely knowledgeable, encouraging, and all-around amazing. With all of her other patients to see, she always made us feel special and took the time to thoroughly explain what was going on and what to expect. She also has an amazing staff and nurse (Maggie) who held our hand along the way. I would recommend her and her team to anyone going through the infertility journey, as I guarantee she will be your shining light throughout the process!"
Ashley Sturgeon - 5 Star Review - 2021
Happy couple with newborn baby in the hospital Happy couple with newborn baby in the hospital

Eggs and embryos do not need to be used immediately. Some patients save their eggs and embryos for later...

In addition to egg freezing, we offer other services that can potentially boost the success rate of an IVF cycle...

Additional Fertility Services Enhancing the IVF Process

Preimplantation Genetic Diagnosis (PGD)

PGD is a type of genetic test performed on embryos before embryo transfer. The procedure monitors for chromosome abnormalities or genetic disorders that could put the pregnancy at risk. By performing PGD, we can ensure that ideal embryos are used during embryo transfer.

Intracytoplasmic Sperm Injection (ICSI)

ICSI is a procedure that increases the chances of successful fertilization when sperm is unable to penetrate the outer layer of the egg. This may be due to poor sperm quality or low sperm motility. During ICSI, a single sperm is injected directly into a viable egg.

Make Your Dreams Come True Patients Share Their Success Stories


Shelby Sykes


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Dr. Kalan is a fertility superhero! He is kind, extremely knowledgeable, patient (this is rare in fertility docs), and treated us like he truly cared about our success. He got to the bottom of our fertility issues and created a customized plan for us that ended in success. We are forever grateful to him and his team. I couldn't recommend him more.

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Sandra McCurdy


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Words cannot express the gratitude we feel for Dr. Winkler. When we first met with her, my husband and I had already been trying to conceive for five years and gone through multiple IVF failures and devastating losses. I was 44 years old and ready to give up. Dr. Winkler was so caring and sympathetic to our situation. She made us feel comfortable, but more importantly, her level of knowledge and expertise gave us the confidence to try one more time. We’re so happy we did! Now we have a beautiful baby girl. Thank you, Dr. Winkler!

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In Vitro Fertilization FAQs We Have the Answers You're Looking For

Couple speaking with doctor

The Los Angeles Reproductive Center can answer any questions you may have about fertility treatments.

In vitro fertilization is a complicated process. It's no surprise we receive so many questions about the procedure, whether it be about success rates, what happens during egg retrieval and embryo transfer, or the potential benefits of ICSI.

Whatever questions you may have about IVF treatment, the Los Angeles Reproductive Center has answers. We've compiled a list of the most common questions about in vitro fertilization, including:

  • Is IVF treatment safe?
  • Will insurance cover IVF treatment?
  • Is the risk of multiple births like twins and triplets high?

Check out our IVF FAQ page, and feel free to contact our fertility clinics if you have any other questions about assisted reproductive technology.

Los Angeles Reproductive Center office

Los Angeles Reproductive Center

Los Angeles Reproductive Center is a state-of-the-art fertility center offering the latest fertility testing and treatment options. Our fertility specialists, Dr. Nurit Winkler and Dr. Marc Kalan, are double board-certified doctors who have been widely recognized for their contributions to reproductive medicine. 

To help all patients achieve their dreams of parenthood, our doctors offer:

  • Compassionate care
  • Flexible payment options
  • Two conveniently located offices

Schedule a consultation online or call us at (818) 946-8051 to learn more about our fertility treatments.

Reach Out To Us Today

Los Angeles Reproductive Center is a unique fertility clinic focused on treating patients like family and built upon the principles of communication, compassion, warmth, openness, and service that accompanies an exceptional pregnancy rate. Contact us today to schedule an appointment.

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