Can You Do PGS Testing on Frozen Embryos? By on May 22, 2020

Digital illustration of frozen embryo

Preimplantation Genetic Screening (PGS) is a test that allows our Encino, CA, fertility doctors to examine the genetic makeup of an embryo to ensure that it contains the appropriate number of chromosomes. PGS embryo testing allows us to identify any genetic abnormalities that could interfere with the success of IVF treatment.

At Los Angeles Reproductive Center, many of our patients use frozen embryos for IVF. Because there are so many benefits to PGS testing, it is common for individuals to ask if PGS testing can also be performed on frozen embryos. Fortunately, PGS testing is still completely viable for frozen embryos and can improve our patients’ chances of having a healthy pregnancy and baby.

How Is PGS Testing Performed?

PGS testing is normally performed as part of IVF treatment. After retrieved eggs have been fertilized, the resulting embryos are tested, usually on day five of development. To perform a PGS test, three to five cells are gently extracted from the embryo. A laboratory technician who has been trained in DNA analysis will examine these cells to confirm that they contain a full set of 46 chromosomes. Within one to seven days, the technician will also be able to identify the gender and determine if the embryo is suitable for transfer.

Testing on Frozen Embryos

Sometimes our Bakersfield patients undergo IVF treatment using frozen embryos, either because they saved embryos from a previous IVF cycle, or because they froze embryos in the past for health or personal reasons. If these embryos did not undergo PGS testing prior to being frozen, it can still be done afterward. In these situations, potential embryos are thawed and then tested as normal. Our fertility doctors can help patients select embryos for transfer, based on the information provided by the PGS test.

It is normal to thaw multiple embryos when performing PGS testing, since we cannot be sure that they will all be genetically and chromosomally normal. Since couples frequently opt to transfer just one or two of the tested embryos, it is reasonable to ask what will happen to remaining embryos that are tested and not transferred. After an embryo has been thawed and tested, it can either be disposed of (if the results of testing were not positive) or it can be refrozen for a future IVF cycle.

Candidates for PGS Testing

A number of our Los Angeles patients can benefit from PGS testing. Candidates for PGS testing of either frozen or fresh embryos include:

  • Women over the age of 35
  • Patients who want to selectively implant a single embryo to avoid the risks of a multiples birth
  • Patients with previous failed IVF cycles
  • Patients with a history of miscarriage, particularly those that are unexplained
  • Patients with a previous chromosomal abnormal pregnancy
  • Couples who have a single-gene disorder or a sex-linked genetic disorder
  • Couples who want to select the gender of their child 

Contact Our Fertility Team

PGS testing provides valuable information that can increase the chance of successful IVF treatment for our patients. If you have more questions about PGS, the fertility doctors at Los Angeles Reproductive Center would be happy to answer them. Send us a message to learn more or call (818) 208-5481 at your earliest convenience.

Los Angeles Reproductive Center office

Los Angeles Reproductive Center

Los Angeles Reproductive Center is a state-of-the-art fertility center offering the latest fertility testing and treatment options. Our fertility specialists, Dr. Nurit Winkler and Dr. Marc Kalan, are double board-certified doctors who have been widely recognized for their contributions to reproductive medicine. 

To help all patients achieve their dreams of parenthood, our doctors offer:

  • Compassionate care
  • Flexible payment options
  • Two conveniently located offices

Schedule a consultation online or call us at (818) 946-8051 to learn more about our fertility treatments.

Reach Out To Us Today

Los Angeles Reproductive Center is a unique fertility clinic focused on treating patients like family and built upon the principles of communication, compassion, warmth, openness, and service that accompanies an exceptional pregnancy rate. Contact us today to schedule an appointment.

Rate, Review & Explore

Social Accounts Sprite
Google map image of our location in 16055 Ventura Blvd Ste 1127 Encino, CA

Encino Office

16055 Ventura Blvd
Ste 1127
Encino, CA 91436

Open Today 8:00am - 5:00pm

Saturdays and Sundays by Appointment.

Google map image of our location in 8305 Brimhall Rd Bldg 1600, Ste 1602 Bakersfield, CA

Bakersfield Office

8305 Brimhall Rd
Bldg 1600, Ste 1602
Bakersfield, CA 93312

Closed Today

Tell us a bit about yourself...

(818) 946-8051 Send a message